Edgard Delvo, 1905-1999

Dr. Edgard San Juan: a feminine look

1Specialist Member of the Brazilian Society of Cardiovascular Surgery. Title of specialist in cardiovascular surgery by the Brazilian Medical Association. Specialist Member of the Brazilian Society of Cardiology. Title of specialist in cardiology by the Brazilian Medical Association. Qualified member of the Department of Cardiac Pacing (DECA).Cardiovascular Surgeon of Real e Benemérita Associaç...

Dmd059121 1890..1905

Subcutaneous injection is an important route of administration for therapeutic proteins that provides several advantages over other modes of parenteral delivery. Despite extensive clinical use, the exact mechanism underlying subcutaneous absorption of proteins is not completely understood, and the accuracy of prediction of absorption of biotherapeutics in humans remains unsatisfactory. This rev...

Dmd065763 1905..1916

Montelukast has been recommended as a selective in vitro and in vivo probe of cytochrome P450 (P450) CYP2C8 activity, but its selectivity toward this enzyme remains unclear. We performed detailed characterization of montelukast metabolism in vitro using human liver microsomes (HLMs), expressed P450s, and uridine 59-diphospho-glucuronosyltransferases (UGTs). Kinetic and inhibition experiments pe...

Phoebus A. Levene, 1905

Mark's Annual Reports, 1905